Hungry-bone-Syndrom

The hungry bone: expected and unexpected.

ate about 3 million new BMU annually, and more than 1 million function at any moment in the whole skeleton. A new BMU is a separate functional unit with regulatory mechanisms for the recruitment, differentiation and activity of precursor cells, osteoclasts, osteoblasts, supporting cells and microvascular bed. It functions in the same sense as nephrons in the kidney7. Osteoclasts and osteoblasts...

Hippo - hungry, hungry for melanoma invasion

The acquisition of invasive properties in melanoma is associated with a high proclivity for metastasis, but the underlying pathways are poorly characterized. The Hippo pathway has an important role in organ size control and is dysregulated in some type of tumors. The present study, "Pro-invasive activity of the Hippo pathway effectors YAP and TAZ in cutaneous melanoma" by Nallet-Staub et al., 2...

Recognition and management of hungry bone syndrome--a case report.

Hungry bone syndrome (HBS) following successful parathyroid surgery is a well described phenomenon. However, few studies have clearly addressed this syndrome or looked at the outcome of perioperative management. We report a case of HBS following successful parathyroid surgery. The perioperative management is discussed and literature pertaining to this interesting case is reviewed.

Rachel Carson Syndrom

For years some ecologists have been convinced that pesticides are contributing to a decline in amphibian species around the globe. From an apparent epidemic of deformed frogs in Minnesota to the near disappearance of yellow-legged frogs from California’s Sierra Nevada Mountains, pesticides have been considered prime suspects. This suspicion is no doubt rooted in the belief by the ecological com...

Das Hepatopulmonale Syndrom